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Hyperplasia

MedGen UID:
43784
•Concept ID:
C0020507
•
Pathologic Function
Synonym: Hyperplasias
SNOMED CT: Hyperplasia (76197007); Cellular proliferation (76197007); Hypercellularity (76197007)
 
Monarch Initiative: MONDO:0005043

Definition

An abnormal increase in the number of cells in an organ or a tissue with consequent enlargement. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyperplasia

Professional guidelines

PubMed

Diagnosis and treatment of primary aldosteronism.
Reincke M, Bancos I, Mulatero P, Scholl UI, Stowasser M, Williams TA
Lancet Diabetes Endocrinol 2021 Dec;9(12):876-892. doi: 10.1016/S2213-8587(21)00210-2. PMID: 34798068
Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society Clinical Practice Guideline.
Speiser PW, Arlt W, Auchus RJ, Baskin LS, Conway GS, Merke DP, Meyer-Bahlburg HFL, Miller WL, Murad MH, Oberfield SE, White PC
J Clin Endocrinol Metab 2018 Nov 1;103(11):4043-4088. doi: 10.1210/jc.2018-01865. PMID: 30272171Free PMC Article
The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline.
Funder JW, Carey RM, Mantero F, Murad MH, Reincke M, Shibata H, Stowasser M, Young WF Jr
J Clin Endocrinol Metab 2016 May;101(5):1889-916. Epub 2016 Mar 2 doi: 10.1210/jc.2015-4061. PMID: 26934393

Recent clinical studies

Etiology

Benign prostatic hyperplasia.
Infante Hernández S, Gómez Rivas J, Moreno Sierra J
Med Clin (Barc) 2024 Oct 25;163(8):407-414. Epub 2024 Jul 15 doi: 10.1016/j.medcli.2024.04.014. PMID: 39013719
Congenital Adrenal Hyperplasia.
Fraga NR, Minaeian N, Kim MS
Pediatr Rev 2024 Feb 1;45(2):74-84. doi: 10.1542/pir.2022-005617. PMID: 38296783
Current Treatment for Benign Prostatic Hyperplasia.
Miernik A, Gratzke C
Dtsch Arztebl Int 2020 Dec 4;117(49):843-854. doi: 10.3238/arztebl.2020.0843. PMID: 33593479Free PMC Article
Neointimal Hyperplasia.
Braga SF, Neves JR, Ferreira J, Carrilho C, Simões JC, Mesquita A
Rev Port Cir Cardiotorac Vasc 2019 Jul-Sep;26(3):213-217. PMID: 31734974
Congenital adrenal hyperplasia: clinical symptoms and diagnostic methods.
Podgórski R, Aebisher D, Stompor M, Podgórska D, Mazur A
Acta Biochim Pol 2018;65(1):25-33. Epub 2018 Mar 15 doi: 10.18388/abp.2017_2343. PMID: 29543924

Diagnosis

Benign prostatic hyperplasia.
Infante Hernández S, Gómez Rivas J, Moreno Sierra J
Med Clin (Barc) 2024 Oct 25;163(8):407-414. Epub 2024 Jul 15 doi: 10.1016/j.medcli.2024.04.014. PMID: 39013719
Benign lesions of the mediastinum.
Gerber TS, Porubsky S
Histopathology 2024 Jan;84(1):183-195. Epub 2023 Nov 21 doi: 10.1111/his.15088. PMID: 37988262
Thymic Parenchymal Hyperplasia.
Suster D, Ronen N, Pierce DC, Suster S
Mod Pathol 2023 Aug;36(8):100207. Epub 2023 May 5 doi: 10.1016/j.modpat.2023.100207. PMID: 37149223
Congenital Adrenal Hyperplasia.
Török D
Exp Suppl 2019;111:245-260. doi: 10.1007/978-3-030-25905-1_12. PMID: 31588535
Review of Prostate Anatomy and Embryology and the Etiology of Benign Prostatic Hyperplasia.
Aaron L, Franco OE, Hayward SW
Urol Clin North Am 2016 Aug;43(3):279-88. doi: 10.1016/j.ucl.2016.04.012. PMID: 27476121Free PMC Article

Therapy

An Updated Systematic Review on Focal Therapy in Localized Prostate Cancer: What Has Changed over the Past 5 Years?
Hopstaken JS, Bomers JGR, Sedelaar MJP, Valerio M, Fütterer JJ, Rovers MM
Eur Urol 2022 Jan;81(1):5-33. Epub 2021 Sep 4 doi: 10.1016/j.eururo.2021.08.005. PMID: 34489140
Post-finasteride syndrome: a surmountable challenge for clinicians.
Traish AM
Fertil Steril 2020 Jan;113(1):21-50. doi: 10.1016/j.fertnstert.2019.11.030. PMID: 32033719
What's New in TIND?
Marcon J, Magistro G, Stief CG, Grimm T
Eur Urol Focus 2018 Jan;4(1):40-42. Epub 2018 Apr 26 doi: 10.1016/j.euf.2018.04.009. PMID: 29705283
Treatment of Concomitant OAB and BPH.
Moss MC, Rezan T, Karaman UR, Gomelsky A
Curr Urol Rep 2017 Jan;18(1):1. doi: 10.1007/s11934-017-0649-z. PMID: 28092069
Lung cancer chemoprevention.
Keith RL
Proc Am Thorac Soc 2012 May;9(2):52-6. doi: 10.1513/pats.201107-038MS. PMID: 22550242Free PMC Article

Prognosis

Randomized Placebo Controlled Trial of Low-Dose Tamoxifen to Prevent Local and Contralateral Recurrence in Breast Intraepithelial Neoplasia.
DeCensi A, Puntoni M, Guerrieri-Gonzaga A, Caviglia S, Avino F, Cortesi L, Taverniti C, Pacquola MG, Falcini F, Gulisano M, Digennaro M, Cariello A, Cagossi K, Pinotti G, Lazzeroni M, Serrano D, Branchi D, Campora S, Petrera M, Buttiron Webber T, Boni L, Bonanni B
J Clin Oncol 2019 Jul 1;37(19):1629-1637. Epub 2019 Apr 11 doi: 10.1200/JCO.18.01779. PMID: 30973790Free PMC Article
The Epidemiology of Benign Prostatic Hyperplasia Associated with Lower Urinary Tract Symptoms: Prevalence and Incident Rates.
Egan KB
Urol Clin North Am 2016 Aug;43(3):289-97. doi: 10.1016/j.ucl.2016.04.001. PMID: 27476122
Best practices in coronary revascularization procedures: are we where we should be?
Taggart DP
Curr Opin Cardiol 2014 Nov;29(6):528-33. doi: 10.1097/HCO.0000000000000111. PMID: 25162752
Endometrial cancer.
Sorosky JI
Obstet Gynecol 2008 Feb;111(2 Pt 1):436-47. doi: 10.1097/AOG.0b013e318162f690. PMID: 18238985
The ageing male.
Schulman C, Lunenfeld B
World J Urol 2002 May;20(1):4-10. doi: 10.1007/s00345-002-0258-3. PMID: 12088188

Clinical prediction guides

Histochemistry in the diagnosis of non-neoplastic gastrointestinal disorders.
Fitzgibbons PL
Semin Diagn Pathol 2018 Nov;35(6):370-380. Epub 2018 Oct 16 doi: 10.1053/j.semdp.2018.10.002. PMID: 30366790
Endocrine Hypertension: A Practical Approach.
Pappachan JM, Buch HN
Adv Exp Med Biol 2017;956:215-237. doi: 10.1007/5584_2016_26. PMID: 27864805
Benign prostatic hyperplasia: clinical manifestations and evaluation.
Santos Dias J
Tech Vasc Interv Radiol 2012 Dec;15(4):265-9. doi: 10.1053/j.tvir.2012.09.007. PMID: 23244722
Grading of chronic synovitis--a histopathological grading system for molecular and diagnostic pathology.
Krenn V, Morawietz L, Häupl T, Neidel J, Petersen I, König A
Pathol Res Pract 2002;198(5):317-25. doi: 10.1078/0344-0338-5710261. PMID: 12092767
The Abrams-Griffiths nomogram.
Lim CS, Abrams P
World J Urol 1995;13(1):34-9. doi: 10.1007/BF00182664. PMID: 7539679

Recent systematic reviews

Minimally Invasive Treatment in Benign Prostatic Hyperplasia (BPH).
Sciacqua LV, Vanzulli A, Di Meo R, Pellegrino G, Lavorato R, Vitale G, Carrafiello G
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338231155000. doi: 10.1177/15330338231155000. PMID: 36794408Free PMC Article
Endometrial hyperplasia as a risk factor of endometrial cancer.
Nees LK, Heublein S, Steinmacher S, Juhasz-Böss I, Brucker S, Tempfer CB, Wallwiener M
Arch Gynecol Obstet 2022 Aug;306(2):407-421. Epub 2022 Jan 10 doi: 10.1007/s00404-021-06380-5. PMID: 35001185Free PMC Article
Benign prostate hyperplasia and nutrition.
Das K, Buchholz N
Clin Nutr ESPEN 2019 Oct;33:5-11. Epub 2019 Aug 12 doi: 10.1016/j.clnesp.2019.07.015. PMID: 31451276
Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis.
Monticone S, D'Ascenzo F, Moretti C, Williams TA, Veglio F, Gaita F, Mulatero P
Lancet Diabetes Endocrinol 2018 Jan;6(1):41-50. Epub 2017 Nov 9 doi: 10.1016/S2213-8587(17)30319-4. PMID: 29129575
Benign prostatic hyperplasia: epidemiology, economics and evaluation.
Vuichoud C, Loughlin KR
Can J Urol 2015 Oct;22 Suppl 1:1-6. PMID: 26497338

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